You will need to use a DSNless connection which can be achieved by using code with the following VBscript:
set rsEvents = Server.CreateObject("ADODB.Recordset")
rsEvents.ActiveConnection = "Driver={MySQL}; DATABASE=databasename;USER=username; PASSWORD=password; Server=127.0.0.1"
...or the following JScript:
var rsEvents = Server.CreateObject("ADODB.Recordset");
rsEvents.ActiveConnection = "Driver={MySQL}; DATABASE=databasename;USER=username; PASSWORD=password; Server=127.0.0.1";